From skin and tissue regeneration to tooth restoration
Emerging pharma and bio industries

Domestic bio-medical device companies with technology in the reverse aging industry are gaining attention. It is emerging as a new industry by expanding its scope beyond simple appearance management to the beauty and bio markets.
According to the pharmaceutical and biotech industry, K-reverse aging companies have recently been making progress in various areas such as tissue regeneration, skin repair, and tooth function restoration, expanding their presence not only in Korea but also in overseas markets.
Market research firm Prescience Research estimates that the global anti-aging market was worth approximately $73 billion last year. Reverse aging technology, which revives the functionality of aging organizations, is seen as an innovation that goes beyond mere cosmetic care.
Shiji Bio, a regenerative medicine specialist, is a representative bio company that implements reverse aging in the field of skin, tissue and bone reconstruction. Its flagship product, Novosys series, is a next-generation bone substitute that combines bone morphogenetic protein ‘rhBMP-2’ and hydroxyapatite (HA), and has proven its effectiveness and safety through more than 100,000 clinical applications worldwide.
In particular, Novosys Putty has obtained all major global licenses, including the U.S. Food and Drug Administration’s (FDA) innovative medical device designation and European CE certification. Based on this, we are leading the global regenerative medicine market by expanding exports to Asia such as China and Vietnam and establishing local subsidiaries.
In the field of skin regeneration, ShijiBio has commercialized DNA-based regeneration solutions to promote autologous collagen production through various product lines, including EGF Skin Booster, PLA Tone, and QB with PN.
MINISH Technology, known for its MINISH solution that restores tooth function and beauty at the same time, is also gaining traction in the reverse aging healthcare market. It provides customized tooth restoration solutions based on biomimetic technology without unnecessary tooth removal after precise scanning of the patient’s oral structure.
In the field of skin lifting devices, JS Medical is leading the global reverse aging trend. POTENZA and DENSITY, which are based on radiofrequency (RF) technology, induce collagen production in a non-invasive or minimally invasive manner and are recognized as effective in revitalizing aging skin.
Potenza, which uses microneedle RF technology to customize treatments according to skin conditions, has sold over 4,000 units globally. It has been approved in the U.S., Europe, and Japan.
“Rejuvenation is an industry that goes beyond anti-aging and overcomes the ‘limitations of aging’ with technology, expanding not only to the beauty industry but also to the medical and bio markets,” said an industry insider. “Rejuvenation solutions that integrate tissue regeneration, functional recovery, and aesthetic improvement will emerge as a new growth engine for the industry in the future.” Jungmo Kang Reporter



